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Low Zinc and Depression: Shocking Discoveries


Most folks probably do not give a whole lot of thought to their zinc intake, but apparently, if your diet is lacking, one of the consequences is depression. Doctors who use an orthomolecular approach to treating depression such as those at the Carl Pfieffer Centers or authors Joan Matthews Larson and Julia Ross have for decades examined their patients' zinc levels. They have found what researchers are only beginning to document - that improving your zinc status from a deficiency state can improve your mental function.

Zinc and depression
The clinical trial evidence for the zinc-depression link is still slim, but researchers do give us cause to believe that the two are related:

* Low levels of zinc are correlated with depression (Maes 1994; Nowak et al. 2005).

* The lower the zinc levels, the worse the depression. One study found that patients with lower serum zinc also tended to have major depression and those with intermediate zinc levels (borderline) tended to have minor depression (Maes et al. 1994).

* Clinical trials improve depression. In a double-blind and placebo-controlled study, patients felt better after six weeks if they were also taking zinc supplements (Nowak et al. 2003 ~ PDF).

* Zinc can complement antidepressant therapy. Patients in the Nowak et al. 2003 study were also on antidepressant medication. The zinc therapy improved their depression above the relief provided by the medication.

* You might be able to increase your brain zinc levels very quickly, today, if you have shock therapy. Nowak et al. (2005) find that shock therapy increases brain levels of zinc in the rat brain. But this is not a great strategy either since it doesn't fix the underlying zinc problem in the longer term.

Low Zinc Body Signs
Doctors may offer their patients a red blood cell zinc test to identify deficiencies but often our bodies give us signs that extra zinc may be in order. Zinc is critical for tissue growth and a low zinc status is often accompanied by:

Soft or thin fingernails
White spots on fingernails
Slow hair growth
Stretch marks on skin

A child's size may be related to his or her zinc status. I have wondered over the years if my extra-small son is extra-small in part due to low zinc in pregnancy. Some children are just small, but as a mom, I do wonder. The good thing in such a case is that more zinc in the diet will help a small child grow.

Dietary sources
Zinc is found most densely in the animal world, particularly in:

* Oysters
* Beef
* Turkey
* Crab
* Lamb
* Duck

Vegetarians tend to rely on grains and legumes for zinc, but only about 15 percent of that zinc will be useable to your body. That percentage will be closer to 10 percent if the food source is a high-phytate, low-phytase food like soy. If you are a vegetarian and concerned about low zinc, read about phytic acidand zinc deficiencies on the phytic acid website. There are simple kitchen preparation techniques to increase your absorption of zinc in the foods you are already eating.

Supplements
If low zinc is aggravating your depression, take a zinc supplement as a short-term strategy. Modify your diet for the long term. But I should note that you should not take zinc supplements if you have no evidence that you are deficient. Too much zinc can become toxic. The amino chelate forms of zinc tend to be absorbed well. The commonly available form of zinc, zinc oxide, is absorbed least well. Zinc supplements are usually about 40 milligrams per day and some include copper because zinc supplementation can reduce copper absorption (DiSilvestro 2004).

The book, Rebuild from Depression, reviews the top seven nutrient deficiencies associated with depression. It reviews how to identify a deficiency, the best form of supplementation, and the best food sources. It is recommended by readers and experts. Read more about the book.



Read more on nutrients and depression
Nutrients and depression
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Magnesium
Iron

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The best book on depression and food I've seen is Rebuild from Depression, by Amanda Rose, who understands the condition from bitter experience.
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Rebuild from Depression is going to be a very important book. Its dissection of the role of diet and nutrition is well-researched and an eye-opener.
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Rebuild from Depression provides real answers for reversing depression caused by common nutritional deficiencies.
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Amanda Rose, Ph.D., is a political scientist and author of "Rebuild from Depression," on the link between nutrient deficiencies and depression. She has been depression-free for over four years, even during the recent pregnancy of her second child. Read her postpartum depression success story.

Depression buster foods




From an analysis of over 5,000 foods in the USDA nutrient database, "depression buster foods" are the foods highest in combination of the seven nutrients most commonly associated with depression. Brains need nutrients to be healthy, particularly those nutrients in these foods for depression. The depression buster food list is published in the book "Rebuild from Depression." A subset are displayed here in the depression buster photo album.

Omega 3 foods




Omega 3 fatty acids are critical for brain health and they are disappearing in the Western diet. You need to consume more Omega 3s and fewer Omega 6s. These photos and descriptions of Omega 3 foods will offer you some guidance. Omega 3 fatty acids are one nutrient that helps fight depression. Read more about the Rebuild philosophy on depression-fighting foods.

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For food science junkies, here is a graph archive based on peer review studies presented on this blog. Each graph has a general explanation and provides a quick link to more detailed discussion.

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Life after depression


There really is life after depression. I am so excited by that point, in fact, that I neglect this blog and find fun/quirky projects to do with my family. We live in the Sequoia National Forest in a house (and former brothel) designed by Irving Gill. My 7-year-old son Frederick and I chronicle our adventures at Gill on the Hill when we're not exploring. Frederick posts some of his homeschool projects at "Frankly Frederick."

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