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Liver and Essential Fatty Acids: One Reason I Like Liver for Depression

Those who know me know that I am a big fan of liver. In fact, liver is a depression buster food and probably in a class of its own providing in large quantities every depression-fighting nutrient in my book except for magnesium. Most foods make the list because they excel in one or two nutrients or in Omega-3 fatty acids. Not liver. It could nearly be your replacement for a multi-vitamin/mineral complex.


Liver is known for its quantities of B vitamins. Adelle Davis, mother of nutrition writers in this country, claimed that liver also has an "anti-stress factor." I am not sure what that is or whether it has been isolated. But something many people don't know about liver is that it can have a pretty nice little dose of Omega-3 fatty acids.

Previously I argued that beef (the muscle, not the liver) is not a great source of Omega-3 fatty acids, even if it comes from cattle fed exclusively on grass. A grass diet improves the level of Omega-3 fatty acids in that steak, but a steak is not Omega-3 nirvana.

In a 1998 study comparing the fatty acid composition of grass fed beef and lamb compared to exclusively grain fed bulls found that 100 grams of grass fed beef liver contained 151 milligrams of EPA and 83 milligrams of DHA, both depression-fighting Omega-3 fatty acids. It also contained 92 milligrams of ALA and 283 milligrams of DPA, both Omega-3 fatty acids that our bodies use to make more EPA.

That 100 grams of liver (about 3 ½ ounces) contains a total of 609 milligrams of Omega-3 fatty acids. That's pretty darned good for a single meal that does not include fish. You can see here that fish is still Omega-3 nirvana.

Even that bull fed a grain diet has some Omega-3 fatty acids in his liver. I compare the liver from the grass fed steer and grain fed bull in the figure above.

When I'm in the middle of a stressful week or in the past when I've hit down-cycles in my depression, I eat liver about three times a week and feel an improvement in my mood and my energy after just a few meals. Liver is cheap and loaded with nutrients. Even organic liver at Whole Foods will provide a very inexpensive dinner for you. Give liver and onions a try to start. I'll ask mom to write out her favorite recipe.

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Amanda Rose, Ph.D., is a political scientist and author of "Rebuild from Depression," on the link between nutrient deficiencies and depression. She has been depression-free for over four years, even during the recent pregnancy of her second child. Read her postpartum depression success story.

Depression buster foods




From an analysis of over 5,000 foods in the USDA nutrient database, "depression buster foods" are the foods highest in combination of the seven nutrients most commonly associated with depression. Brains need nutrients to be healthy, particularly those nutrients in these foods for depression. The depression buster food list is published in the book "Rebuild from Depression." A subset are displayed here in the depression buster photo album.

Omega 3 foods




Omega 3 fatty acids are critical for brain health and they are disappearing in the Western diet. You need to consume more Omega 3s and fewer Omega 6s. These photos and descriptions of Omega 3 foods will offer you some guidance. Omega 3 fatty acids are one nutrient that helps fight depression. Read more about the Rebuild philosophy on depression-fighting foods.

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For food science junkies, here is a graph archive based on peer review studies presented on this blog. Each graph has a general explanation and provides a quick link to more detailed discussion.

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There really is life after depression. I am so excited by that point, in fact, that I neglect this blog and find fun/quirky projects to do with my family. We live in the Sequoia National Forest in a house (and former brothel) designed by Irving Gill. My 7-year-old son Frederick and I chronicle our adventures at Gill on the Hill when we're not exploring. Frederick posts some of his homeschool projects at "Frankly Frederick."

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